Comparative analysis between fasting and postprandial apolipoprotein B and total cholesterol/high-density lipoprotein-cholesterol ratio for atherosclerosis risk prediction in type 2 diabetes mellitus subjects of central India

Background: Type 2 diabetes mellitus (Type DM), characterized by a relative insulin deficiency or resistance, is associated with cluster of metabolic abnormalities, which includes glucose intolerance, hypertension, unique dyslipidemia, procoagulant state, and an increase in macrovascular diseases. Aims Objectives: The present study was conducted to correlate between fasting postprandial apolipoprotein B total cholesterol/high-density lipoprotein-cholesterol (TC/HDL-C) ratio for predicting the risk atherosclerosis T2DM subjects. Materials Methods: Sixty clinically diagnosed cases (age group 35–65 years duration more than 5 years) were included sixty age- sex-matched healthy subjects taken as controls. In both groups, we measured well lipid profile, comprised serum TC, triglycerides (TGs), HDL-C, low-density lipoprotein cholesterol (LDL-C), B. Ratio calculated TC/HDL-C state. statistical analysis done using students unpaired’-test. Results: results showed significantly increased levels TGs, LDL-C, apo compared those state (P<0.05). HDL-C level lower that Postprandial are condition type Conclusion: findings suggest B, cardiovascular factor can be utilized simple marker utilizing parameters profile state.Thus, Apolipoprotein number LDL particles (for atherosclerosis) circulation routinely estimated assessment